An odontogenic tumor is a neoplasm of the cells or tissues that initiate odontogenic processes examples include. Maxillary odontogenic myxoma involving the maxillary sinus. Myxoma as stated is a tumor present near the heart. We present herein the case of a 24yearold patient, with an incidental finding of a. It preferably locates in posterior mandibular regions, followed by the incisors, maxillary and. This study evaluated the literature concerning the surgical management of odontogenic myxoma, and reports the longterm outcome of a. Clinical and radiological features of odontogenic myxoma of the jaws dentomaxillofacial radiology, vol. The lesion may evolve from a dental germ dental papilla or follicle or from the periodontal membrane, and therefore is invariably be related to the coronal or radicular portion of teeth. Odontogenic myxoma is a rare tumor in the head and neck. Odontogenic myxoma, arising from the mesenchymal portion of the tooth germ, is a locally invasive benign tumor and is generally associated with unerupted or missing tooth.
An odontogenic myxoma of the maxilla with an aggressive clinical course is presented. Clinicopathologic analysis of 14 cases of odontogenic myxoma and. Extragnathic odontogenic sinonasal myxoma with mitotic. The odontogenic myxoma is an uncommon benign odontogenic tumor arising from embryonic connective tissue associated with tooth formation. As a myxoma, this tumor consists mainly of spindle shaped cells and scattered collagen fibers distributed through a loose, mucoid material. Odontogenic myxoma om is defined as a benign odontogenic tumor of mesenchymal.
Odontogenic tumors represents a broad spectrum of lesions ranging from benign to malignant to dental hamartomas all arising from odontogenic residues, that is, the odontogenic epithelium, ectomesenchyme with variable amounts of dental hard tissues formed in the same sequence as in normal tooth development. Case report with reconstructive considerations odontogenic myxoma. If you have problems viewing pdf files, download the latest version of adobe reader. Odontogenic myxomas are considered to be a benign odontogenic tumor with locally aggres sive behavior, nonmetastasizing neoplasm of the jaw bones. The description of extragnathic odontogenic sinonasal myxoma is rarely reported in the literature.
It is nonencapsulated, arises from odontogenic ectomesenchyme, develops solely in the jaws, and represent a small percentage of odontogenic tumor overall. Lo muzio l, nocini p, favia g, procaccini m, mignogna md. On examination, there was firm swelling in the anterior tooth region and both. This is a pdf file of an unedited manuscript that has been accepted for publication. Odontogenic myxoma of the jaws is a rare slow growing, benign tumor of mesenchymal tissue origin and is characterized grossly by mucoid or gelatinous graywhitish tissue that replaces the cancellous bone and expands the cortex. More common in mandible than maxilla 23 in mandible clinical features. These tumors are usually located on the atrial septum. Peripheral odontogenic myxoma is a rare odontogenic tumor representing an extra osseous counterpart of central odontogenic myxoma. When involving the maxilla, odontogenic myxomas can expand to inside the maxillary sinus, and are then diagnosed later only after having grown to larger sizes. It represents approximately 3 6% of all odontogenic tumors. Odontogenic myxoma is a rare slow growing, benign, locally aggressive tumor of ectomesenchymal origin with or without odontogenic epithelium, comprising 3%. The evidence for its odontogenic origin arises from its almost exclusive location in the toothbearing areas of the jaws, its occasional association with missing or unerupted teeth and the presence of. Odontogenic myxoma, odontogenic fibromyxoma, maxilla 1. Pdf odontogenic myxoma om is a locally aggressive, benign, slowgrowing tumor arising from mesenchyme andor odontogenic epithelium.
Deliverska, department of oral and maxillofacial surgery, faculty of dental medicine, medical university, sofia, bulgaria issn. Odontogenic myxoma is a benign odontogenic tumor with locally aggressive behavior, and is relatively rare in the oral cavity. They are often asymptomatic and present as painless swelling. The aim of this paper is to report a case of odontogenic myxoma that affected the right maxilla and maxillary sinus. Odotogenic myxoma is a benign tumor which presents in 3% to 6% of all odontogenic tumors. Epidemiology typically seen in the 2nd to 3rd decades of life slightly earlier than ameloblastomas. This paper reports a case of odontogenic myxoma in a child treated with a. Odontogenic myxoma a rare case and diagnostic and therapeutic challenges elitsa g. The odontogenic myxoma is a relatively rare benign tumor occurring in the jaws. Odontogenic myxoma om is a benign, locally inva sive and aggressive, nonmetastasizing neoplasm of the jaw bones. This is a case report of odontogenic myxoma in a 32 year old female patient and the treatment rendered to her. Despite the benign nature of this lesion, there is a high.
Click on the link to view a sample search on this topic. A novel cause of cherubism, journal of oral and maxillofacial surgery 2014, doi. Odontogenic myxomas are benign but locally aggressive neoplasms found almost exclusively in the jaws and arise only occasionally in other bones. Introduction odontogenic myxomas om are benign tumours first described in the literature by thoma and goldman in 1947 1. The molar and bicuspid regions of jaw are frequently involved.
Odontogenic myxoma of maxilla in an atypical location. When the lesion is large and when presenting in a difficult location, aggressive. Odontogenic myxoma international journal of oral health and. The tumour arose in a 53yearold patient, recurred two times after extended maxillectomy and ultimately caused the patients death by uncontrollable local disease with infiltration of the cranial cavity. An irregular soft tissue mass lesion is seen arising from right maxillary bone alveolar process, measuring 6 x 4. Odontogenic myxoma can be found most often in young adults aged 2535 years although lesions may occur over a lifetime, reporting the lowest. Full text pdf 5725k abstracts references17 a case of odontogenic myxoma of the mandible is reported. Kleiber gm, skapek sx, lingen m, reid rr, odontogenic myxoma. Central odontogenic fibroma cof is an uncommon benign neoplasm composed by varying amounts of inactivelooking odontogenic epithelium embedded in a neoplastic mature and fibrous stroma 112. To document the clinical, pathologic, and behavioral features of odontogenic myxomas. Pubmed is a searchable database of medical literature and lists journal articles that discuss odontogenic myxoma.
According to the world health organization who, om. There is no evidence in the literature in regard to the best treatment approach, in terms of conservative or aggressive surgery, for this type of tumor. Department of oral and maxillofacial surgery, faculty of dental medicine, medical. Odontogenic myxoma is a rare, benign intraosseous tumor.
Ameloblastoma, a type of odontogenic tumor involving ameloblasts. Odontogenic myxomas om are tumors derived from embryonic mesenchymal elements of dental anlage. A 52yearold woman was referred with painless swelling in the anterior portion of the mandible. Odontogenic myxoma genetic and rare diseases information. Odontogenic myxoma of the maxilla a rare case report. According to the world health organization who, they originate from odontogenic ectomesenchyme, with or without odontogenic epithelium 2 3. Odontogenic myxoma om is a rare entity of slowly growing benign neoplasm of ectomesenchymal origin, comprising of 36% of all odontogenic tumors that.
Most cases diagnosed in 2nd 4th decades but wide age range of occurrence between 1 to 73 years more common in women sites. The present case documents the resective and reconstructive management of a patient with a moderately large myxoma of the mandible. Odontogenic myxoma is an uncommon benign mesenchymal odontogenic tumor arising from the dental papilla, follicle, or the periodontal ligament. Click on the link above to view the information page.
There are currently no clear surgical management guidelines for odontogenic myxoma, and a variety of approaches may be used. Benign odontogenic lesions are rare entities but are very important due to their locally aggressive nature. Odontogenic myxoma is even rarer in children than in adults. Odontogenic myxoma of maxilla sivakumar g, kavitha b. Odontogenic myxoma definition of odontogenic myxoma by. Odontogenic myxoma in an adolescent patient report of a. A myxoma new latin from greek muxa for mucus is a myxoid tumor of primitive connective tissue. Pdf odontogenic myxoma is a rare intraosseous neoplasm, which is benign but locally aggressive. Odontogenic myxoma om is a benign intraosseous neoplasia, not very frequent, 1 but with high infiltrative potential that makes it a locally invasive tumor. Odontogenic myxoma ddmfr oral and maxillofacial radiology. This report describes a case of odontogenic myxoma producing diffusely dispersed calcified products in a pattern. Odontogenic myxoma om is a benign intraosseous tumor, but locally invasive, having a high rate of recurrence. Case report in this presentation, the patient with a peripheral odontogenic myxoma of the posterior maxillary gingiva was presented with histological findings following surgery, and the clinical. A clinical, radiologic, immunohistochemical, and ultrastructural study.
Myxoma is mostly seen in adult or elderly animals and although there is no sex predilection, it is supposed that doberman pincher and german shepherd dogs have a racial predisposition 8. Odontogenic myxoma is a rare benign but locally aggressive odontogenic tumor. Available formats pdf please select a format to send. Odontogenic myxoma is a rare benign tumour of the jaw and characteristically presents as a slow, painless, bony expansion with resultant facial deformity. Report of two cases sridhar p reddy 1, ananth naag 1, bina kashyap 2 1 department of oral and maxillofacial surgery, st joseph dental college and hospital, duggirala, eluru, andhra pradesh, india 2 department of oral pathology, st joseph dental college and hospital, duggirala, eluru, andhra pradesh, india. Odontogenic myxomas om, also called odontogenic fibromyxomas, are rare tumours of the jawbones. Clinicoradiographic examination of odontogenic myxoma with.
Majority of myxomas that occur are present on the left side of the heart. Odontogenic myxomas are rare tumors that involve the mandible or maxilla and account for 36% of odontogenic tumors 2. Educational video created by unmc college of dentistry class of 2016 dental students. It is most commonly associated with an unerupted tooth and probably arises from the mesenchymal portion of the tooth germ 1. An odontogenic myxoma in anterior portion of the mandible. Ameloblastoma, odontogenic myxoma, keratocystic odontogenic tumor and central giant cell lesion should be considered in the differential diagnosis 39. Odontogenic myxoma in an 8yearold girl journal of oral and.
It presents local invasiveness and tendency to recurrence. It is most commonly found in the heart and is the most common primary tumor of the heart in adults but can also occur in other locations. Case report with reconstructive considerations spencer, k. Surgical management of an uncommon cutaneous myxoma. There were 14 patients with diagnosis of odontogenic myxoma om. Microscopically, an ameloblastic fibroma is composed of a connective tissue background that appears to recapitulate dental papilla, resembling stellate reticulum 7. Treatment, symptoms, causes, complications, diagnosis. Odontogenic myxoma is a rare and locally invasive benign neoplasm found exclusively in jaws. A 29 year old female patient attending ambula tory practice of the maxillofacial surgery clinic for assessment and treatment. An expanded odontogenic myxoma in maxilla stomatologija. They are benign tumours that can be locally invasive and aggressive, but seldom undergo malignant transformation and do not give rise to metastases. This presentation describes a unique case of odontogenic myxoma of anterior maxilla in an 8yearold girl with emphasis on its diagnosis and. The odontogenic myxoma is a rare, benign tumor that does not shed metastasis and involves the maxillomandibular complex.
Odontogenic myxoma of the mandible ramya sree s1, vardendra g kulkarni2, chandrashekhar hr3, shivamurthy kc4 abstract. It can occur at any age but most commonly in the second and third decades of life. Pdf odontogenic myxoma is a benign odontogenic tumor with locally aggressive behavior, and is relatively rare in the oral cavity. Odontogenic myxoma om is a benign, but locally invasive, neoplasm occurring in the jaws. Pdf odontogenic myxoma of the mandible researchgate. The swelling had been present for 15 years and enlarged gradually. Odontogenic myxoma is a rare, benign, locally aggressive and non metastasizing neoplasm which is believed to arise from the odontogenic ectomesenchyme and bears a close microscopic resemblance to mesenchymal portion of a tooth germ. Odontogenic myxoma odontogenic myxofibroma odontogenic fibromyxoma epidemiology. The childrens hospital boston has an information page on odontogenic tumors in general. Pdf odontogenic myxomas are benign but locally aggressive neoplasms found almost exclusively in the jaws and arise only occasionally in other bones.